Summary of: Griffith SD, Miksad RA, Calkins G, You P, Lipitz NG, Bourla AB, Williams ER, George DJ, Schrag D, Khozin S, Capra WB, Taylor MD, Abernethy AP. Characterizing the feasibility and performance of real-world tumor progression end points and their association with overall survival in a large advanced non-small cell lung cancer dataset. JCO Clin Cancer Informatics. 2019.
Flatiron’s follow-up study expands the previous pilot to evaluate real-world progression (rwP) abstraction at scale. This study confirmed relatively high completeness and agreement for the approach used in curating rwP events for an EHR dataset of over 30,000 patients with advanced non-small cell lung cancer.